882 research outputs found
Proces starzenia się ludności Polski według prognoz z lat 60. i 90.
Materiały na Konferencję Jubileuszową
Łódź, 27-28 listopada 1997r
The Role of Grass Feeding in Improving Oxidative Stability and Increasing Vitamin B\u3csub\u3e12\u3c/sub\u3e Content of Beef and Veal
The objective of this study was to investigate the influence of grass feeding of cattle on the decontamination capacity against free radical (DCAFR) and vitamin B12 content of beef and veal. The meat samples from intensively (26 cattle, final weight 485±9 kg, concentrate feeding) and ecologically (25 heifers, final weight 472±32 kg, and 28 calves, final weight 260±24 kg, pasture grazing) managed cattle groups were investigated. The DCAFR was colorimetric assessed by examining damage to 1.4 benzoquinone. Vitamin B12 was analyzed by high performance liquid chromatography. Data indicate that the oxidative stability of meat samples from ecological management were significant (p \u3c 0.05) higher (1.39 mg/ ml sec) compared to samples from intensive management (1.09 mg/ ml sec). Meat from pasture grazed animals proves to be an especially good source of vitamin B12, which was present in the high amount in beef (3.24 mg/100g) and veal (3.32 mg/100g). This paper establishes the importance of grass feeding at the levels of the relevant essential nutrients supplied by meat
Non-Gaussian Distributions in Extended Dynamical Systems
We propose a novel mechanism for the origin of non-Gaussian tails in the
probability distribution functions (PDFs) of local variables in nonlinear,
diffusive, dynamical systems including passive scalars advected by chaotic
velocity fields. Intermittent fluctuations on appropriate time scales in the
amplitude of the (chaotic) noise can lead to exponential tails. We provide
numerical evidence for such behavior in deterministic, discrete-time passive
scalar models. Different possibilities for PDFs are also outlined.Comment: 12 pages and 6 figs obtainable from the authors, LaTex file,
OSU-preprint-
Vortex-unbinding and finite-size effects in Tl2Ba2CaCu2O8 thin films
Current-voltage (-) characteristics of TlBaCaCuO thin
films in zero magnetic field are measured and analyzed with the conventional
Kosterlitz-Thouless-Berezinskii (KTB) approach, dynamic scaling approach and
finite-size scaling approach, respectively. It is found from these results that
the - relation is determined by the vortex-unbinding mechanism with the
KTB dynamic critical exponent . On the other hand, the evidence of
finite-size effect is also found, which blurs the feature of a phase
transition.Comment: Typo corrected & reference adde
Trace and antitrace maps for aperiodic sequences, their extensions and applications
We study aperiodic systems based on substitution rules by means of a
transfer-matrix approach. In addition to the well-known trace map, we
investigate the so-called `antitrace' map, which is the corresponding map for
the difference of the off-diagonal elements of the 2x2 transfer matrix. The
antitrace maps are obtained for various binary, ternary and quaternary
aperiodic sequences, such as the Fibonacci, Thue-Morse, period-doubling,
Rudin-Shapiro sequences, and certain generalizations. For arbitrary
substitution rules, we show that not only trace maps, but also antitrace maps
exist. The dimension of the our antitrace map is r(r+1)/2, where r denotes the
number of basic letters in the aperiodic sequence. Analogous maps for specific
matrix elements of the transfer matrix can also be constructed, but the maps
for the off-diagonal elements and for the difference of the diagonal elements
coincide with the antitrace map. Thus, from the trace and antitrace map, we can
determine any physical quantity related to the global transfer matrix of the
system. As examples, we employ these dynamical maps to compute the transmission
coefficients for optical multilayers, harmonic chains, and electronic systems.Comment: 13 pages, REVTeX, now also includes applications to electronic
systems, some references adde
(Anti)Proton and Pion Source Sizes and Phase Space Densities in Heavy Ion Collisions
NA44 has measured mid-rapidity deuteron spectra from AA collisions at
sqrt{s}=18GeV/A at the CERN SPS. Combining these spectra with published proton,
antiproton and antideuteron data allows us to calculate, within a coalescence
framework, proton and antiproton source sizes and phase space densities. These
results are compared to pion source sizes and densities, pA results and to
lower energy (AGS) data. The antiproton source is larger than the proton source
at sqrt{s}=18GeV/A. The phase space densities of pions and protons are not
constant but grow with system size. Both pi+ and proton radii decrease with
transverse mass and increase with sqrt{s}. Pions and protons do not freeze-out
independently. The nature of their interaction changes as sqrt{s}, and the
pion/proton ratio increases.Comment: 4 pages, Latex 2.09, 3 eps figures. Changes for January 2001. The
proton source size is now calculated assuming a more realistic Hulthen,
rather than Gaussian, wavefunction. A new figure shows the effect of this
change which is important for small radii. A second new figure shows the
results of RQMD calculations of the proton source size and phase density.
Because of correlations between position and momentum coalesence does not
show the full proton source size. The paper has been streamlined and
readability improve
Methods for determining the CO2 removal capacity of enhanced weathering in agronomic settings
Recent analysis by the IPCC suggests that, across an array of scenarios, both GHG emissions reductions and various degrees of carbon removal will be required to achieve climate stabilization at a level that avoids the most dangerous climate changes in the future. Among a large number of options in the realm of natural climate solutions, atmospheric carbon dioxide removal (CDR) via enhanced silicate weathering (EW) in global working lands could, in theory, achieve billions of tons of CO2 removal each year. Despite such potential, however, scientific verification and field testing of this technology are still in need of significant advancement. Increasing the number of EW field trials can be aided by formal presentation of effective study designs and methodological approaches to quantifying CO2 removal. In particular, EW studies in working lands require interdisciplinary “convergence” research that links low temperature geochemistry and agronomy. Here, drawing on geologic and agronomic literature, as well as demonstration-scale research on quantifying EW, we provide an overview of (1) existing literature on EW experimentation as a CO2 removal technique, (2) agronomic and geologic approaches to studying EW in field settings, (3) the scientific bases and tradeoffs behind various techniques for quantifying CO2 removal and other relevant methodologies, and (4) the attributes of effective stakeholder engagement for translating scientific research in action. In doing so, we provide a guide for establishing interdisciplinary EW field trials, thereby advancing the verification of atmospheric CO2 in working lands through the convergence of geochemistry and agronomy
Influence of CRTC1 Polymorphisms on Body Mass Index and Fat Mass in Psychiatric Patients and the General Adult Population.
IMPORTANCE There is a high prevalence of obesity in psychiatric patients, possibly leading to metabolic complications and reducing life expectancy. The CREB-regulated transcription coactivator 1 (CRTC1) gene is involved in energy balance and obesity in animal models, but its role in human obesity is unknown. OBJECTIVE To determine whether polymorphisms within the CRTC1 gene are associated with adiposity markers in psychiatric patients and the general population. DESIGN, SETTING, AND PARTICIPANTS Retrospective and prospective data analysis and population-based samples at Lausanne and Geneva university hospitals in Switzerland and a private clinic in Lausanne, Switzerland. The effect of 3 CRTC1 polymorphisms on body mass index (BMI) and/or fat mass was investigated in a discovery cohort of psychiatric outpatients taking weight gain-inducing psychotropic drugs (sample 1, n = 152). The CRTC1 variant that was significantly associated with BMI and survived Bonferroni corrections for multiple comparison was then replicated in 2 independent psychiatric samples (sample 2, n = 174 and sample 3, n = 118) and 2 white population-based samples (sample 4, n = 5338 and sample 5, n = 123 865). INTERVENTION Noninterventional studies. MAIN OUTCOME AND MEASURE Difference in BMI and/or fat mass between CRTC1 genotype groups. RESULTS Among the CRTC1 variants tested in the first psychiatric sample, only rs3746266A>G was associated with BMI (Padjusted = .003). In the 3 psychiatric samples, carriers of the rs3746266 G allele had a lower BMI than noncarriers (AA genotype) (sample 1, P = .001; sample 2, P = .05; and sample 3, P = .0003). In the combined analysis, excluding patients taking other weight gain-inducing drugs, G allele carriers (n = 98) had a 1.81-kg/m2 lower BMI than noncarriers (n = 226; P < .0001). The strongest association was observed in women younger than 45 years, with a 3.87-kg/m2 lower BMI in G allele carriers (n = 25) compared with noncarriers (n = 48; P < .0001), explaining 9% of BMI variance. In the population-based samples, the T allele of rs6510997C>T (a proxy of the rs3746266 G allele; r2 = 0.7) was associated with lower BMI (sample 5, n = 123 865; P = .01) and fat mass (sample 4, n = 5338; P = .03). The strongest association with fat mass was observed in premenopausal women (n = 1192; P = .02). CONCLUSIONS AND RELEVANCE These findings suggest that CRTC1 contributes to the genetics of human obesity in psychiatric patients and the general population. Identification of high-risk subjects could contribute to a better individualization of the pharmacological treatment in psychiatry
The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence
Funding: This work was funded by the European Research Council [http://erc.europa.eu/], AJPB (STRIFE Advanced Grant; C-2009-AdG-249793). The work was also supported by: the Wellcome Trust [www.wellcome.ac.uk], AJPB (080088, 097377); the UK Biotechnology and Biological Research Council [www.bbsrc.ac.uk], AJPB (BB/F00513X/1, BB/K017365/1); the CNPq-Brazil [http://cnpq.br], GMA (Science without Borders fellowship 202976/2014-9); and the National Centre for the Replacement, Refinement and Reduction of Animals in Research [www.nc3rs.org.uk], DMM (NC/K000306/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgments We thank Dr. Elizabeth Johnson (Mycology Reference Laboratory, Bristol) for providing strains, and the Aberdeen Proteomics facility for the biotyping of S. cerevisiae clinical isolates, and to Euroscarf for providing S. cerevisiae strains and plasmids. We are grateful to our Microscopy Facility in the Institute of Medical Sciences for their expert help with the electron microscopy, and to our friends in the Aberdeen Fungal Group for insightful discussions.Peer reviewedPublisher PD
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